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Questions and AnswersQuestion No.: 18899 Submitted By: Bob Submitted on: April 7, 2009 Subject: antioxidants Question: Can you explain, at least in theory, what antioxidants do beneficially to LDL. And, is there any validity to (synthetic) antioxidants actually being PRO-oxidant? What are your recommendations? Thanks.... Dr. Cinque's Answer: Well, keep in mind that I can repeat what I have heard and read, and I suspect that only a few biochemists really understand it beyond a crude, elementary level. But LDL can oxidize, which means react with oxygen, which changes it and makes it an irritant and perhaps a provcateur of plaque formation, and the antioxidants (like Vitamin C, E, lutein, etc.) provent these oxidations. Apparently, there are conditions in which antioxidants can act as pro-oxidants, and that's where some of the controversy about taking antioxidants arises. I take a middle of the road approach, meaning that I do take antioxidant supplements, but not in mega, Linus Pauling doses. For instance for Vitamin C, I take 500 mgs, plus whatever I get from my food. That assures my getting the lion's share of the benefit but without any risk of harm. I think it's a sensible approach for most people. |
