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Question No.: 18882
Submitted By: Don Hjelmseth
Submitted on: April 5, 2009
Subject: natural antidepressant

Question:
For the past three years plus I've been on Lexapro 10 mg. It works on the mild depression but has destroyed my ability to have an orgasm or ejaculations. You sell vitamins, etc. and I'm curious about 5 HTP and SAMe, but know nothing about their possible help on my problem. I've taken Cymbalta 30 mg and Wellbutrin XL 150 mg to no avail. Also, tried St. John's Wort for roughly three months and then that wore off and back to the Lexapro. Would appreciate some suggestions. Thank, Don Hjelmseth

Dr. Cinque's Answer:
There are many natural supplements you could try, but my first choice and my starting point for a natural antidepressant is still SAM-e. I think much higher of SAM-e than 5htp, which you also mentioned. The stanard dose of SAM-e is 800 mgs daily in divided doses, and it would be safe to take it in tandem with the pharmaceutical drug you are taking and then after a time to start backing off the pharmaceutical drug.